Igepal CO-630, also known by its CAS number 68412-54-4, is a nonionic surfactant belonging to the family of alkylphenol ethoxylates. It is a member of the Igepal CO series, which are commonly used as emulsifiers, wetting agents, dispersants, and detergents in a wide variety of industrial and laboratory applications.
Chemical Structure and Composition
Igepal CO-630 is typically identified as a nonylphenol ethoxylate, consisting of a nonylphenol backbone with an average of six ethylene oxide units per molecule. This structure gives the compound amphiphilic properties, meaning it contains both hydrophilic (water-attracting) and hydrophobic (water-repelling) segments—ideal for reducing surface tension and promoting solubility between otherwise immiscible substances.
Key Properties
– Appearance: Clear to slightly hazy liquid or waxy solid
– Solubility: Soluble in water and various organic solvents
– Surface Activity: Excellent wetting and emulsifying capability
– HLB (Hydrophilic-Lipophilic Balance): Approximately 10–12, depending on the formulation
These characteristics make Igepal CO-630 versatile in a range of technical and industrial processes.
Common Applications
1. Laboratory Reagent:
Igepal CO-630 is frequently used in biological and chemical laboratories as a lysis agent for breaking cell membranes and extracting proteins or nucleic acids, especially in DNA/RNA isolation protocols.
2. Industrial Cleaning and Detergents:
Its surfactant properties make it a component in industrial cleaning agents, where it aids in removing oils, greases, and particulates from machinery, tools, and surfaces.
3. Paints, Coatings, and Inks:
In the paint and coatings industry, Igepal CO-630 serves as a dispersant and emulsifier to help maintain uniformity and improve the spreadability and durability of products.
4. Textile and Leather Processing:
It is used as a wetting agent or detergent in textile and leather manufacturing, assisting in dyeing and scouring processes.
5. Pesticide Formulations:
Igepal CO-630 is used as a carrier or emulsifier in agricultural chemical formulations, helping active ingredients mix evenly with water and improving delivery to plants or soil.
6. Cosmetic and Personal Care Applications (non-edible):
In some formulations, it may be used in shampoos, conditioners, and other topical products for its emulsifying and solubilizing properties.
Handling and Safety
While effective in numerous applications, Igepal CO-630 should be handled with care. Exposure to skin or eyes may cause irritation, and inhalation of mists or vapors should be avoided. Always consult the product’s Safety Data Sheet (SDS) before use and adhere to recommended personal protective measures.
Safety Considerations:
– Protective Equipment: Gloves, goggles, lab coat
– Storage Conditions: Store in a cool, dry, and well-ventilated area
– Environmental Concerns: Like many alkylphenol ethoxylates, it may pose environmental hazards, especially in aquatic ecosystems. Proper disposal and containment measures should be observed.
Conclusion
Igepal CO-630 (CAS: 68412-54-4) is a powerful nonionic surfactant widely valued in laboratory and industrial environments for its solubilizing, emulsifying, and wetting capabilities. Its broad range of applications—from cell lysis in research labs to formulation support in manufacturing—makes it a staple in many technical processes, provided it is handled responsibly and safely.
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